class=”article_teaser__2t5do”>After missing out on a chance for the quadruple, Al Hain-Cole expects Guardiola's men to move one step closer to the title with a big win over Villa

Manchester City will be determined to bounce back when they travel to Villa Park to take on Aston Villa in Wednesday’s Premier League clash.

The Citizens saw their hopes of completing an unprecedented quadruple dashed by last weekend’s FA Cup semi-final defeat against Chelsea, but are still in line to win a treble.

Aston Villa vs Manchester City Latest Odds

Having also suffered a surprise 2-1 home defeat against Leeds in their last league match, they are available at 4/11 (1.36) with bet365 to get back on track with a morale-boosting victory here.

Dean Smith’s team has won just one of their last six fixtures in all competitions and are 8/1 (9.00) outsiders to upset the leaders by coming out on top, or priced at 15/4 (4.75) to earn a creditable draw.

Aston Villa vs Manchester City Team News

Trezeguet has joined Jack Grealish and Wesley on the sidelines after suffering a season-ending knee injury against Liverpool, while Morgan Sanson will face a late fitness test.

Kevin De Bruyne is likely to be out for a month with the ankle injury he picked up against Chelsea, with Sergio Aguero also an injury doubt.

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Aston Villa vs Manchester City Preview

With their quadruple dream now over for another season, Pep Guardiola’s men will be fired up to ensure their title bid does not derail after looking like an inevitability for so long.

While their eight-point lead is still commanding, two defeats in the last five league matches does leave a glimmer of hope for a chasing pack led by second-placed Manchester United.

However, they will certainly back themselves to take the points against a side that has struggled without the inspirational Grealish – winning just twice in eight matches in his absence.

Aston Villa vs Manchester City Tips and Predictions

All in all, odds of 20/21 (1.95) seem generous on a motivated City side winning by at least two clear goals for their eighth league game in nine on the road, as well as a sixth match in seven against Villa.

All odds correct at time of writing. Please gamble responsibly.